STABLE BIOACTIVE GLASS FORMULATIONS
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United States of America
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Issued Date -
Nov 7, 2024
app pub date -
Apr 22, 2024
filing date -
Apr 22, 2024
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Abstract
An aqueous dentifrice formulation, comprising: a bioactive glass exhibiting at least one of: a hydrolytic resistance of glass grains (HGB) of at most 4, when measured by International Organization for Standardization section 719 (ISO 719); a weight loss of 5 wt. % or less after soaking 5 g of the bioactive glass in powder form in 100 mL of deionized water for 7 days at 37° C.; an XRD spectrum substantially free of crystalline phase after soaking 5 g of the bioactive glass in powder form in 100 mL of deionized water for 7 days at 37° C.; or any combination thereof; wherein, when the bioactive glass is contacted with artificial saliva, the bioactive glass forms a bioactive crystalline phase. A method of using the aqueous dentifrice formulation to remineralize enamel of the tooth, treat caries of the tooth, treat dentin hypersensitivity of the tooth, or any combination thereof.
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