A METHOD AND SYSTEM FOR DETERMINING A QUANTITATIVE COMPOSITION RATIO OF A MICROBIAL STRAIN MIXTURE FOR USE IN A FERMENTATION PROCESS
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United States of America
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Nov 7, 2024
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Jul 26, 2022
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Jul 26, 2022
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Abstract
A method of determining a quantitative composition ratio of a microbial strain mixture for use in a fermentation process. The method includes repeatedly performing method cycles, each method cycle comprising the steps of: selecting a set of plurality of microbial strain mixtures having different quantitative composition ratios; concurrently performing fermentation processes for each selected microbial strain mixture; determining, for each of the fermentation processes, at least one performance indicator of the microbial strain mixture; and providing the at least one performance indicator for each of the fermentation processes to a statistical model which is configured to optimize a predefined objective function, wherein the statistical model is configured to determine, based on said determined performance indicators, a subsequent set of plurality of microbial strain mixtures with different quantitative composition ratios for selection in a next cycle.
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