Importance

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Abstract

A process for manufacturing a microfluidic device including:

a) providing a first substrate having a first surface including a first flat part and a first concavity and a second substrate having a second surface including a second flat part and an optional second concavity,b) coating at least one of the first surface and the second surface with a coating composition including i) a monomer A including one moiety represented by CH2=CR1R2 wherein R1 represents H or CH3 and R2 represents —COO— or —CONH—, and a non-ionic hydrophilic moiety;ii) a monomer B including two or more moieties represented by CH2=CR1R2 wherein R1 represents H or CH3 and R2 represents —COO— or —CONH—, and a non-ionic hydrophilic moiety;iii) optionally a photoinitiator;iv) optionally a diluent; c) evaporating the diluent if present, and forming a liquid coating;d) contacting the substrates so as to obtain an assembly in which the first flat part and the second flat part contact each other to define a microfluidic structure between the first and the second surfaces, wherein the microfluidic structure includes the first concavity and the optional second concavity; ande) at least partially irradiating the assembly with light having a wavelength between 200 and 800 nm to crosslink the liquid coating to bond the first flat part and the second flat part and obtain a crosslinked coating on at least the first concavity.

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First Claim