GENERATING IRREVERSIBLE-ELECTROPORATION AND RADIOFREQUENCY-ABALTION (IRE/RFA) WAVEFORMS

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United States of America

APP PUB NO 20250057582A1
SERIAL NO

18936179

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Abstract

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A method of delivering a combined irreversible electroporation and radio frequency (IRE/RFA) signal during ablation that includes receiving a selection of a ratio of IRE/RFA energy and a selection of an interleaved sequence of a combined IRE/RFA waveform. The interleaved sequence includes one or more adapted IRE square pulses formed by adapting generated biphasic IRE square pulses to IRE pulses having a final shape and repetition rate using a biphasic pulse shaper, and one of more RFA cycles formed from converting the generated biphasic IRE square pulses into a RF sinusoidal signal using a harmonic filter. The interleaved sequence is generated by interleaving, into a single waveform, the one or more adapted IRE square pulses with one or more cycles of the converted RF sinusoidal signal. The combined IRE/RFA output signal is outputted to a catheter electrode inside a patient's heart for application to a target tissue location.

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Patent Owner(s)

Patent OwnerAddress
BIOSENSE WEBSTER (ISRAEL) LTDYOKNEAM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Altmann, Andres Claudio Haifa, IL 370 11471
Govari, Assaf Haifa, IL 961 30271

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