Expanding the Molecular Processing and Biosensing Capabilities of a Single-Construct Quantum Dot-Based Biosensor By Selectively Controlling Energy Transfer Pathways

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20250084459A1
SERIAL NO

18776176

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Abstract

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An energy transfer platform involves a CdSe/ZnS core-shell quantum dot (QD) scaffold having four additional components: terbium metal chelate, ruthenium(II)-phenanthroline, AlexaFluor 647, and Cy5.5. These are positioned in a self-assembled fashion on the QD surface through the utilization of peptide-PNA and DNA bioconjugate linkers. The modular platform can operate to sense multiple different events or targets simultaneously, including sensing of genetic moieties and enzymatic targets.

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Patent Owner(s)

Patent OwnerAddress
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVYNAVAL RESEARCH LABORATORY 875 NORTH RANDOLF STREET SUITE 1425 ARLINGTON VA 22203 22203

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chiriboga, Matthew Washington, US 1 0
Diaz, Sebastian A Washington, US 5 0
Hastman, David A Washington, US 1 0
Hildebrandt, Niko Ontario, CA 8 9
Hooe, Shelby L Washington, US 2 0
Medintz, Igor L Washington, US 43 177
Susumu, Kimihiro Washington, US 28 63

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