BIOMARKERS FOR PREDICTING PRETERM BIRTH DUE TO PRETERM PREMATURE RUPTURE OF MEMBRANES (PPROM) VERSUS IDIOPATHIC SPONTANEOUS LABOR (PTL)
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United States of America
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Issued Date -
Mar 13, 2025
app pub date -
Jun 17, 2024
filing date -
Jun 17, 2024
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Abstract
The present invention provides compositions and methods for predicting the probability of preterm birth in a pregnant female. The present invention provides a composition comprising one or more biomarkers selected from the group consisting of the biomarkers set forth in FIGS. 1 and 2 and Tables 1 through 3, 6 through 38, and 44 through 68. In one embodiment, the invention provides a method of determining probability for preterm birth in a pregnant female, optionally preterm birth associated with preterm premature rupture of membranes (PPROM) or preterm birth associated idiopathic spontaneous labor (PTL), the method comprising measuring in a biological sample obtained from the pregnant female one or biomarkers selected from one or more of the biomarkers set forth in FIGS. 1 and 2 and Tables 1 through 3, 6 through 38, and 44 through 68 to determine the probability for preterm birth in said pregnant female.
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