METHOD OF MANUFACTURING STOPPER WITH SEPTUM FOR MEDICAL CONTAINER, THE STOPPER AND POLYMER COMPOSITION FOR THE SEPTUM
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United States of America
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Issued Date -
Mar 20, 2025
app pub date -
Sep 13, 2024
filing date -
Sep 13, 2024
priority date (Note) -
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status (Latency Note)
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Abstract
The present invention provides a manufacturing method for a stopper used in medical containers, the stopper having a septum and a housing supporting the septum, the manufacturing method comprising firstly creating the septum using a first molding process with a thermoplastic elastomer composition; then creating the housing using a second molding process with a plastic composition, by the second molding process the septum being pre-compressed in a radial direction perpendicular to a needle penetration direction of the septum; and subjecting the stopper to a steam sterilization, wherein after the septum experiences the steam sterilization, the septum exhibits a residual pre-compression level of 12% to 30% in the radial direction compared to when the septum is uncompressed, and the residual pre-compression level is measured based on a thickness or average diameter of the septum.
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