Synthesis for Borylated Amino Acid Compositions Comprising TC220 and TC221 For Use in Boron Neutron Capture Therapy and Methods Thereof
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United States of America Patent
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Issued Date -
Mar 27, 2025
app pub date -
Aug 16, 2024
filing date -
Aug 16, 2024
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Abstract
Borylated Amino Acid compositions comprising tyrosine derivatives TC220 and TC221 and improved methods of making TC220 and TC221 are disclosed herein. Consequently, the TC220 and/or TC221 can be scaled up to commercial scale and administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders, and other disease by utilizing a Neutron Capture Therapy modality.
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