BIFUNCTIONAL LINKER COMPRISING METAALLYLSILANE AND METHOD FOR PREPARING SAME
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United States of America
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Issued Date -
Apr 10, 2025
app pub date -
Nov 21, 2022
filing date -
Nov 21, 2022
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Abstract
The present invention relates to a metaallylsilane-based linker compound, a method for preparing same, and the like. The present invention makes it possible to prepare a nanoprobe in which two or more functional molecules are incorporated in a silica nanoparticle that is modified with the linker compound by means of a one-pot process through a continuous bioorthogonal reaction. The nanoprobe of the present invention can be incorporated in a targeting ligand capable of delivering a drug to a specific location, a fluorescent dye for molecular imaging, a radioactive isotope, a magnetic substance, a drug for treatment, and the like, and thus can be used for in vivo molecular imaging, theranostics, and the like.
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