A METHOD FOR REPRODUCIBLE APTAMER SELECTION USING CLOSED SEQUENCE SOLUTION SPACES
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United States of America
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Apr 10, 2025
app pub date -
Jan 20, 2023
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Jan 20, 2023
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Abstract
In the field of aptamers, closed sequence solution space libraries for aptamer selection. Also, methods for selecting aptamers for binding to target molecules in which biological samples derived from individuals that differ by phenotype are contacted with the library of aptamers and the aptamer oligonucleotides that bound to the target molecules are covered. Further, methods of treating a disorder or a disease of a subject in which the disorder or disease is diagnosed using the library of aptamers and the subject is treated.
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