Indolo-,1,2-dihydroindolo-, and 1,2,6,7-tetrahydroindolo [1,7-ab][1,5] benzodiazepines

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United States of America Patent

PATENT NO 4186199
SERIAL NO

05956904

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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What is disclosed are ##STR1## wherein X is hydrogen, halogen or trifluoromethyl; Y is hydrogen, halogen or trifluoromethyl; R is hydrogen, loweralkyl, cycloalkyl, phenyl, halophenyl, furyl, pyridinyl, 4-methylpiperazin-1-ylethyl or phenylloweralkyl; R.sup.1 is hydrogen; n and m are independently 0 or 1, but n is not 0 when m is 1, and the bonds between ring positions 1 and 2 and between positions 6 and 7 are respectively saturated when n and m are 1 and are unsaturated when n and m are 0; pharmaceutically acceptable acid addition salts thereof; methods of preparing said compounds; pharmaceutical compositions including said compounds; methods of treatment using the compounds; and intermediates therefor. These compounds are useful as analgesic and anti-inflammatory agents, as well as intermediates for the preparation of other pharmaceutically active compounds.

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Patent Owner(s)

  • AMERICAN HOECHST CORPORATION, A CORP. OF DE.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fortunato, James M Somerville, NJ 5 135
Glamkowski, Edward J Warren, NJ 113 760

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