Pharmaceutical preparation and use of 4-hydroxy-2-quinolinone-3-carboxylic acid esters

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United States of America Patent

PATENT NO 4190659
SERIAL NO

05807898

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Abstract

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Disclosed are compounds which are 4-hydroxy-2-quinolinone-3-carboxylic acid esters, e.g., 1-methyl-4-hydroxy-2-quinolinone-3-carboxylic acid ethyl ester, useful as anti-allergic agents and intermediates for 1-alkyl-4-alkoxy-quinolin-2(1H)-ones, and prepared by reacting an isatoic anhydride with an alkali metal salt of a malonic ester.

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Patent Owner(s)

  • SANDOZ, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hardtmann, Goetz E Morristown, NJ 13 41

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