Method of producing antibodies

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United States of America Patent

PATENT NO 4196265
SERIAL NO

05933092

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Continuous cell lines of genetically stable fused cell hybrids capable of producing large amounts of monoclonal antibodies against specific viruses and their antigenic determinants have been developed. The cell lines are fused cell hybrids between viral antibody producing cells and myeloma cells. Fused cell hybrids between influenza virus-primed mouse spleen cells and mouse myeloma cells can be maintained indefinitely in culture and continue to produce large amounts of anti-influenza antibody.

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Patent Owner(s)

  • THE WISTAR INSTITUTE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Croce, Carlo M Philadelphia, PA 177 3475
Gerhard, Walter U Philadelphia, PA 1 366
Koprowski, Hilary Wynnewood, PA 32 798

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