Sustained release therapeutic compositions
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United States of America Patent
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-
Oct 7, 1980
Grant Date -
N/A
app pub date -
Jun 14, 1979
filing date -
Jun 14, 1979
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Shaped pharmaceutical tablets, lozenges, suppositories and other solid dosage unit forms which have a prolonged and regular release pattern of a therapeutically active medicament incorporated therein, wherein the shaped dosage unit comprises a carrier base material of hydroxypropylmethylcellulose or a mixture thereof with up to 30% ethylcellulose and/or up to 30% sodium carboxymethylcellulose and wherein the carrier base material is subjected to hydrolysis and oxidation so as to generate thereon a desired minimum concentration of carbonyl and carboxyl groups, and then admixed and shaped with a therapeutically active medicament.
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