Alkyl and cycloalkylthiophenylalkylaminoalkanols, their salts and the preparation thereof

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United States of America Patent

PATENT NO 4228187
SERIAL NO

05718534

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Abstract

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Amino-alcohols of the formula ##STR1## wherein R.sub.1 represents either a linear or branched chain alkyl radical having 1 to 4 carbon atoms, or a cycloalkyl radical having 5 or 6 carbon atoms; R.sub.2 represents a lower alkyl radical having 1 or 2 carbon atoms; R.sub.3 represents a linear or branched chain alkyl radical having 3 to 10 carbon atoms which radical is optionally substituted by phenyl; R.sub.4 represents hydrogen, or, together with R.sub.3 and the adjacent nitrogen atom, a heterocyclic nucleus of the piperidine type and the corresponding non-toxic salts of said amino-alcohols; preparation of the above and their use as antispasmodic, peripheral vasodilatory and anti-hypertensive agents and as an agent having a protective activity against anoxia of the myocardium.

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Patent Owner(s)

  • CONTINENTAL PHARMA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gillet, Claude L Brussels, BE 11 90
Lambelin, Georges E Brussels, BE 9 100
Roba, Joseph L Wanlin, BE 8 97

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