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Abstract

Natural heteropolysaccharide, specifically hexuronyl hexosaminoglycane sulfate and, a process to obtain it, which substantially provides for the following steps: (a) hydrolysis of an animal organ with a proteolytic enzyme, in water; (b) precipitation of the hydrolyzed product with a water miscible solvent; (c) solubilization of the precipitate in a solution of a salt of a strong mineral acid; (d) addition of a quaternary ammonium halide to form a soluble complex and a precipitate which is separated; (e) precipitation of such complex by dilution with water; (f) isolation and solubilization of the precipitated complex in a salt solution according to step (c); (g) precipitation of the final product with a water miscible solvent and drying thereof; Such compound is utilized as active principle in pharmaceutical compositions, particularly suitable for the prevention of thrombotic states.

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First Claim