Bradykinin-inhibiting tripeptide derivatives

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United States of America Patent

PATENT NO 4242329
SERIAL NO

06058333

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Abstract

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Tripeptide derivatives of the formula H-D-X-Phe-Arg-Y in which X is selected from the group consisting of Pro and Phe Y is selected from the group consisting of O--R.sub.1 and NH--R.sub.2 in which R.sub.1 is selected from the group consisting of straight, branched and cyclic alkyl group with 1-12 C atoms, and R.sub.2 is selected from the group consisting of H, straight, branched and cyclic alkyl group with 1-12 C atoms, and physiologically acceptable salts thereof. A process for producing said tripeptide derivatives by synthesis and purification methods which are known in the peptide chemistry. Pharmaceutical preparations comprising said tripeptide derivatives.

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  • AB KABI

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arielly, Salo Kungsbacka, SE 6 82
Claeson, Karl G Lidingo, SE 9 127
Simonsson, Leif R Hisings-Backa, SE 6 94

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