Processes for the preparation of glyoxal-2-oxims
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United States of America Patent
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Jan 6, 1981
Issued Date -
N/A
app pub date -
Aug 20, 1979
filing date -
Mar 9, 1978
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Novel derivatives of glyoxal-2-oxim represented by the chemical formula ##STR1## wherein R is hydrogen or a lower alkyl or phenyl group, are provided in accordance with the present invention. These derivatives are prepared by reacting the corresponding isoxazole-5-carbaldehyde with nitromethane in the presence of a metal alkoxide, or the corresponding 5-acetylisoxazole with a nitrate. They have anti-inflammatory and/or analgesic activities.
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