Artificial beta cell
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United States of America Patent
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-
Jan 20, 1981
Issued Date -
N/A
app pub date -
Feb 12, 1979
filing date -
Jan 22, 1975
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
An artificial beta cell regulates blood glucose concentration in a subject by continuously analyzing blood from the patient and deriving a computer output signal to drive a pump which infuses insulin at a rate corresponding to the signal. A value of blood glucose concentration from the analyzed blood is used by a computer to determine a rate of change of this concentration which in turn is used to derive a projected blood glucose level. A sigmoidal relationship between the projected blood glucose concentration and the rate of infusion is used to determine the actual rate of infusion required and hence an output signal is fed to the pump to create this actual rate of insulin infusion.
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