US Patent No: 4,246,261
Number of patents in Portfolio can not be more than 2000
Additives enhancing topical corticosteroid action
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Jan 20, 1981
Issued date -
Aug 9, 1979
filing date -
06/065,332
serial no -
Expired
status
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Abstract
Composition and method for enhancing therapeutic effects of corticosteroids to alleviate the symptoms of inflammation and exfoliation such as psoriasis, eczema, seborrheic dermatitis and other inflammatory skin conditions consisting of a solution, cream, lotion, ointment or gel containing as two active ingredients a corticosteroid and an additive are disclosed. The therapeutic composition may include one or more of corticosteroids typically present in a total amount of from 0.01 to 2 percent and one or more of hydroxy acids or related compounds present in a total amount from 0.01 to 2 percent by weight of the total composition. Topical application of the therapeutic composition in a solution, cream, lotion, gel or ointment has been found to achieve a substantial increase in antiinflammatory action of corticosteroids.
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First Claim
Related Publications
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
- Assignment data not available. Check USPTO
International Classification(s)
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Inventor(s)
| Inventor Name | Address | # of filed Patents | Total Citations |
|---|---|---|---|
| Van, Scott Eugene J | Abington, PA | 145 | 2125 |
| Yu, Ruey J | Chalfont, PA | 164 | 2422 |
Cited Art
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Patent Citation Ranking
Forward Cites
| Patent Info | (Count) | # Cites | Year |
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| 5,385,938 Method of using glycolic acid for treating wrinkles | 69 | 1992 | |
| 5,665,776 Additives enhancing topical actions of therapeutic agents | 30 | 1993 | |
| 5,389,677 Method of treating wrinkles using glycalic acid | 57 | 1993 | |
| 5,702,688 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | 17 | 1993 | |
| 5,470,880 Method of using citric acid for the treatment of wrinkles | 38 | 1994 | |
| 5,422,370 Method of using 2-hydroxypropanoic acid (lactic acid) for the treatment of wrinkles | 36 | 1994 | |
| 5,547,988 Alleviating signs of dermatological aging with glycolic acid, lactic acid or citric acid | 42 | 1994 | |
| 5,670,541 Method of treating wrinkles using gulonic acid or gulonolactone | 1 | 1995 | |
| 5,668,177 Method of treating wrinkles using tartaric acid | 1 | 1995 | |
| 5,591,774 Method of treating wrinkles using malic acid | 3 | 1995 | |
| 5,589,505 Method of treating wrinkles using quinic acid or quinolactone | 7 | 1995 | |
| 5,561,155 Method of treating wrinkles using galacturonic acid or galacturonolactone | 1 | 1995 | |
| 5,561,159 Method of treating wrinkles using tropic acid | 1 | 1995 | |
| 5,550,154 Method of treating wrinkles using glucuronic acid or glucuronolactone | 1 | 1995 | |
| 5,716,992 Method of using mucic acid or mucolactone for treating wrinkles | 1 | 1995 | |
| 5,677,339 Method of using mandelic acid for treating wrinkles | 1 | 1995 | |
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| 5,674,899 Method of using lactic acid for treating wrinkles | 1 | 1995 | |
| 5,674,903 Method of using citric acid for treating wrinkles | 1 | 1995 | |
| 5,670,542 Method of using glucuronic acid or glucronolactone for treating wrinkles | 1 | 1995 | |
| 5,670,543 Method of using pantoic acid or pantolactone for treating wrinkles | 1 | 1995 | |
| 5,656,665 Method of using quinic acid or quinolactone for treating wrinkles | 6 | 1995 | |
| 5,656,666 Method of using ribonic acid or ribonolactone for treating wrinkles | 1 | 1995 | |
| 5,654,340 Method of using gulonic acid or gulonolactone for treating wrinkles | 2 | 1995 | |
| 5,652,267 Method of using saccharic acid or saccharolactone for treating wrinkles | 1 | 1995 | |
| 5,650,436 Method of using galactonic acid or galactonolactone for treating wrinkles | 1 | 1995 | |
| 5,650,437 Method of using benzilic acid for treating wrinkles | 1 | 1995 | |
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| 5,583,156 Method of treating wrinkles using ribonic acid or ribonolactione | 2 | 1995 | |
| 5,580,902 Method of treating wrinkles using ethyl pyranate | 4 | 1995 | |
| 5,578,644 Method of treating wrinkles using isocitric acid | 1 | 1995 | |
| 5,574,067 Method of treating wrinkles using gluconic acid or gluconolactone | 1 | 1995 | |
| 5,571,841 Method of treating wrinkles using mandelic acid | 2 | 1995 | |
| 5,565,487 Method of treating wrinkles using galactonic acid or galactonolactone | 2 | 1995 | |
| 5,561,153 Method of treating wrinkles using mucic acid or mucolactone | 1 | 1995 | |
| 5,561,156 Method of treating wrinkles using methyllactic acid | 1 | 1995 | |
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| 5,554,651 Method of treating wrinkles using citramalic acid | 1 | 1995 | |
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| 5,889,054 Method of using beta hydroxy acids for treating wrinkles | 18 | 1997 | |
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| 5,856,357 Method for treating wrinkles using certain alpha hydroxyacids | 4 | 1997 | |
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| 6,384,079 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | 8 | 1999 | |
| 6,191,167 Pharmaceutical compositions containing hydroxycarboxylic acid and/or ketocarboxylic acids and methods of using the same | 10 | 1999 | |
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| 5,948,418 Sulfur-based amides and bis-amides useful against skin disorders | 5 | 1997 | |
| 6,025,347 Steroid esters useful against skin disorders | 6 | 1998 | |
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| 4,971,800 Method and compositions for enhancing the cutaneous penetration of pharmacologically active agents | 36 | 1989 | |
| 5,051,260 Method and composition for enhancing the cutaneous penetration of pharmacologically active agents | 39 | 1990 | |
| 5,045,317 Enhancing the cutaneous penetration of pharmacologically active agents | 32 | 1990 | |
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| 5,254,343 Reduction of cutaneous atrophy | 14 | 1992 | |
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| 5,759,555 Cosmetic formulation and method for amelioration of skin keratoses and striae distensae | 6 | 1996 | |
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| 5,407,958 Therapeutic skin composition | 21 | 1993 | |
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| 5,561,166 Urea/lactate topical compositions for dry skin | 2 | 1993 | |
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| 5,798,388 Method and composition for treating mammalian diseases caused by inflammatory response | 6 | 1996 | |
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Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |