Maytansinoids and use
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United States of America Patent
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Feb 3, 1981
Grant Date -
N/A
app pub date -
Oct 18, 1979
filing date -
Oct 27, 1978
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Novel maytansinoids of the formula: ##STR1## wherein R is an alicyclic hydrocarbon group of 3 to 10 carbon atoms, phenyl or heterocyclic group, which may optionally be substituted, and A is an alkylene group of 1 to 4 carbon atoms or a bond, provided that A means said alkylene group when attached to a N atom in said heterocyclic group R, have antimicrobial, antimitotic and antitumor activities.
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