Maytansinoids, pharmaceutical compositions thereof and method of use thereof
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United States of America Patent
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Apr 28, 1981
Grant Date -
N/A
app pub date -
Jul 23, 1980
filing date -
Jul 31, 1979
priority date (Note) -
Expired
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Abstract
Novel maytansinoid compounds of the formula: ##STR1## wherein X is H or Cl, R.sup.1 is an alkyl group of 2 to 4 carbon atoms and R.sup.2 is a lower alkyl group or an unsubstituted or substituted phenyl or aralkyl group, have antimitotic, antitumor and antimicrobial activities.
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