5-Unsubstituted-9,9-dimethyl-6,7-benzomorphans

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United States of America Patent

PATENT NO 4268673
SERIAL NO

05928862

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Abstract

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The invention is concerned with certain novel 6,7-benzomorphan derivatives having analgesic and/or morphine-antagonistic properties of the formula ##STR1## wherein each R is a lower alkyl group; R.sub.1 is a hydrogen atom, or an alkyl, haloalkyl, alkenyl, haloalkenyl, alkinyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, cycloalkenylalkyl, cycloalkylidenealkyl, aralkyl, heteroarylalkyl or heterocycloalkylalkyl group; R.sub.2 is a hydrogen atom or a hydroxy, alkoxy, alkoxyalkoxy or acyloxy group. Such 6,7-benzomorphans may be in the form of their optically active enantiomers and/or their therapeutically acceptable salts. Methods for producing such 6,7-benzomorphan derivatives, and novel intermediates useful for such production are also disclosed and form part of the invention.

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Patent Owner(s)

  • ACF CHEMIEFARMA N.V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akkerman, Antony M Amsterdam, NL 5 35
van, Leeuwen Geertruida C Amsterdam, NL 1 21

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