Thiopropionamides, and the pharmaceutical compositions
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United States of America Patent
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Aug 11, 1981
Grant Date -
N/A
app pub date -
Sep 25, 1978
filing date -
Sep 28, 1977
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention relates to omega-mercaptopropionylamides, the nitrogen atom of which is included as a ring atom of a cyclic amino acid. The application also discloses a process for producing said compounds which comprises reacting an omega-mercaptopropionic acid, or a functional derivative thereof, with a cyclic amino acid. This invention further relates to pharmaceutical compositions incorporating such an omega-mercaptopropionylamide as active ingredient together with a pharmaceutically-acceptable carrier or vehicle, and a method of employing said compounds. They find a use in human therapy, namely, as antihypertensive agents.
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