Pharmaceutical compositions containing urea
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United States of America Patent
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-
Sep 22, 1981
Grant Date -
N/A
app pub date -
Jun 15, 1979
filing date -
Jun 16, 1978
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Pharmaceutical compositions for application topically or by suppository comprise: (a) a medicament, preferably protected from degradation by moisture by being presented in small particles of a waxy material, (b) from 5% to 40% of an inclusion compound of urea with a straight-chain aliphatic compound, preferably a fatty acid or alcohol, (c) up to 50% of an inert insoluble powder such as starch, (d) from 25% to 90% of an inert carrier, components (a), (b) and (c) being dispersed in (d). The compositions have good storage stability and a smooth texture.
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