20-O-Acylmaytansinoids
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United States of America Patent
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-
Oct 13, 1981
Grant Date -
N/A
app pub date -
Jan 15, 1980
filing date -
Jan 31, 1979
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Novel 20-demethoxy-20-acyloxymaytansinoids representable by the formula: ##STR1## [wherein X is chlorine or hydrogen; R.sub.1 is hydrogen or acyl group; R.sub.2 is acyl group] are produced from 20-demethoxy-20-hydroxymaytansinoids by means of acylation. The compounds are useful as antifungal, antiprotozoal or antitumor agent.
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