Process for the preparation of purified bacterial membranal proteoglycans
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United States of America Patent
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Oct 27, 1981
Grant Date -
N/A
app pub date -
Dec 13, 1979
filing date -
Dec 19, 1978
priority date (Note) -
Expired
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Abstract
This invention relates to a process for the preparation of purified bacterial membranal proteoglycans. The process comprises at least one step in which crude proteoglycans are treated in aqueous medium with a base or a hypobromite, followed by elimination of the excess reactant and the insoluble residue, the purified proteoglycans being present in aqueous solution. The thus obtained purified proteoglycans may be used as immunity adjuvants in vaccines without causing side-effects such as pyrogenic reactions.
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