Benzamides with local anaesthetic and antiarrhythmic activity, salts, and method of preparation thereof and pharmaceutical compositions therefrom
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United States of America Patent
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Dec 15, 1981
Grant Date -
N/A
app pub date -
Nov 18, 1980
filing date -
Dec 7, 1979
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Benzamides of formula I ##STR1## are described, in which R=CH.sub.3, Cl or COOCH.sub.3 ; R' is a member selected from the group of dialkylamine, pyrrolidine, piperidine, and morpholine radicals. CH.sub.2 R' is in position ortho, meta, or para with respect to the carbonyl group; and their salts thereof with pharmaceutically acceptable acids are described. The novel compounds exhibit local anaesthetic and antiarrhythmic activity.
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