Imidazo[1,2-a]pyridines having anti-ulcer activity
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United States of America Patent
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Jan 19, 1982
Grant Date -
N/A
app pub date -
Oct 30, 1980
filing date -
Nov 14, 1979
priority date (Note) -
Expired
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Abstract
Imidazo[1,2-a]pyridine of the formula ##STR1## in which R represents H or CH.sub.3 and R.sub.1 represents H or CH.sub.3 which can be used in human therapy as inhibitors of gastric secretion. The compounds are prepared by reacting a methylisothiourea of the formula ##STR2## with methylamine in aqueous solution of dimethyl formamide or in hydroalcoholic solution, at temperatures between 0.degree. and 50.degree. C.
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