Chemotherapeutically active maytansinoids from Trewia nudiflora
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United States of America Patent
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Feb 2, 1982
Grant Date -
N/A
app pub date -
Jan 27, 1981
filing date -
Jan 27, 1981
priority date (Note) -
Expired
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Abstract
A novel group of maytansinoid compounds has been discovered in the seed tissue of Trewia nudiflora. They are represented by the general formula ##STR1## and are all characterized by a distinguishing methoxy group on the C-15 carbon. These isolates have proven to be effective in causing the remission of one or more types of malignancies.
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