Process for the purification of ursodeoxycholic acid
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United States of America Patent
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Feb 23, 1982
Grant Date -
N/A
app pub date -
Jul 11, 1980
filing date -
Jul 12, 1979
priority date (Note) -
Expired
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Abstract
A mixture of ursodeoxycholic acid and of chenodeoxycholic acid as well as of their salts and esters is reacted with a silylating agent in a suitable anhydrous organic solvent; the corresponding silyl-derivatives thus obtained are separated by crystallization and pure ursodeoxycholic acid is recovered from the corresponding silyl-derivatives in the usual manner.
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