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Abstract

A method for preserving a large section of biological tissue with a curable polymer such as an acrylic resin by impregnating the large section with the polymer and pressing the impregnated large section between flat plates. These plates are further separated near their edges by an elastomeric material, thereby providing a flat cell in which the opposing cut surfaces of the impregnated large section abut the inner surfaces of the cell plates. Thereafter the cell is filled up with uncured polymer. The polymer is then cured, the plates moving toward each other due to the polymer shrinkage during curing. Finally, the plates are removed. The resulting plastinated sheet is a permanently-preserved large section of biological tissue whose tissue water is completely replaced by a cured polymer, the sheet having a uniform thickness and smooth, even surfaces.

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First Claim