Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration
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United States of America Patent
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Mar 23, 1982
Grant Date -
N/A
app pub date -
Aug 22, 1980
filing date -
Aug 22, 1980
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A novel formulation of bacampicillin for oral administration is disclosed. Microcapsules comprising an acid addition salt of bacampicillin coated with a mixture of ethyl cellulose:water-soluble or water-permeable filler material are suspended in a buffered vehicle having a pH of at least 6.9. The novel suspension is characterized by palatable taste, surprisingly good stability and enhanced bioavailability after oral administration. The novel suspension is well suited for multiple dose oral administration. The preferred filler material is hydroxypropyl cellulose.
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Family
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