Cyano-ureas, cyano-thioureas and their preparation methods
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Jun 22, 1982
Grant Date -
N/A
app pub date -
Nov 14, 1980
filing date -
Mar 14, 1979
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
The invention relates to cyano-urea and cyano-thiourea derivatives characterized by structures of formulas (a),(b),(c) and (d): ##STR1## in which R is 2-mercapto-ethyl radical or 2-((4-methyl-5-imidazolyl) thiomethyl) ethyl radical. The invention relates to the manufacture of cyano-ureas and cyano-thioureas. The compounds of invention: N-2-((4-methyl-5-imidazolyl)thiomethyl) ethyl-N'-imino-cyano-urea,N-2-((4-methyl-5-imidazolyl)thiomethyl) ethyl N'-imino-cyano-thiourea, as well as their carbonyl and thio-carbonyl tautomers are histamine antagonists in the H.sub.2 receptors which inhibit the secretion of gastric acid. They can be used therapeutically for the treatment of gastric and duodenal ulcers.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully