Optical sensor of plasma constituents
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United States of America Patent
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Aug 17, 1982
Issued Date -
N/A
app pub date -
Apr 28, 1980
filing date -
Aug 2, 1978
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A system for monitoring low molecular weight compounds in blood plasma in the body by optical means includes a chamber which can be inserted into the blood stream and which contains specific receptor sites for the plasma constituent to be analyzed. The chamber interior is isolated from the blood by a dialysis membrane which permits the plasma constituents to diffuse into the chamber. A competing ligand for the receptor sites is placed within the chamber, but due to its relatively large molecular size the competing ligand cannot escape through the dialysis membrane into the bloodstream. Light emitted or absorbed by the competing ligand gives a measure of the concentration of the selected low molecular weight compounds in the blood.
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