Oxime ethers, their preparation and pharmaceutical compositions containing them
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United States of America Patent
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Oct 5, 1982
Grant Date -
N/A
app pub date -
Jul 11, 1979
filing date -
Jul 25, 1978
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Oxime ether derivatives of the formula (I): ##STR1## wherein Het is a monocyclic heteroaromatic group containing two hetero atoms at least one of which is nitrogen, or a bicyclic heteroaromatic group containing one or two hetero atoms at least one of which is nitrogen, Ar is a phenyl or a 5- or 6-membered monocyclic heteroaromatic group, and R is an alkyl, alkenyl, alkynyl, cyanoalkyl, carbamidoalkyl or aminoalkyl group, or N-oxides thereof, have anti-ulcer activity in the gastro-intestinal tract of mammals.
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