Fermentation process of preparing demethyl maytansinoids

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Nov 30, 1982
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Aug 7, 1981
filing date
Mar 24, 1978

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Expired

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Abstract

Novel demethylmaytansinoids representable by the formula: ##STR1## (wherein X is Cl or H; R.sub.1 is H or acyl group) are produced from maytansinoids by means of enzymic transformation. The demethylmaytansinoids are useful as antifungal, antiprotozoal or antitumor agents.

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TAKEDA CHEMICAL INDUSTRIES LTD	A CORP OF JAPAN OSAKA

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C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....

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Inventor Name	Address	# of filed Patents	Total Citations
Asai, Mitsuko	Osaka, JP	23	1458
Izawa, Motowo	Hyogo, JP	8	1689
Nakahama, Kazuo	Kyoto, JP	16	1218

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Fermentation process of preparing demethyl maytansinoids

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United States of America Patent

06290943

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PATENT NO	4361650
SERIAL NO	06290943
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06290943

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