Maytansinoid compound
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United States of America Patent
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-
Dec 7, 1982
Grant Date -
N/A
app pub date -
Sep 17, 1980
filing date -
Sep 21, 1979
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Antibiotic C-15003 PND of the formula: ##STR1## wherein R is H or alkanoyl containing not more than 5 carbon atoms is produced by contacting a maytansinoid compound with a culture broth, inclusive of a processed matter derived therefrom, of a microorganism belonging to one of the genera Streptomyces and Chainia which is able to transform said maytansinoid compound into Antibiotic C-15003 PND. Antibiotic C-15003 PND is useful as antitumor, antifungal or antiprotozoal agent.
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