Blood-coagulation-promoting products and methods of preparing them
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United States of America Patent
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Dec 21, 1982
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N/A
app pub date -
May 27, 1980
filing date -
May 27, 1980
priority date (Note) -
Expired
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Abstract
Blood-coagulation-promoting products substantially free of thrombin are prepared from human blood plasma by contacting a human blood plasma fraction containing coagulation Factors II, VII, IX and X with an anion exchanger to adsorb the coagulation Factors, which are subsequently eluted from the anion exchanger. The eluate is treated to generate a substance having Factor VIII Inhibitor Bypassing Activity and being substantially free of thrombin, and activated Factor X.
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