Dipyricamole sustained release forms comprising lacquer-coated particles and the preparation thereof
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United States of America Patent
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-
Jan 4, 1983
Grant Date -
N/A
app pub date -
Dec 31, 1980
filing date -
Jan 12, 1980
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
This invention relates to a composition for the sustained release of dipyridamole which comprises (i) spheroid particles comprised of dipyridamole or crystallized salts thereof and pharmacologically acceptable acid or acid substance, and (ii) a coating surrounding said spheroid particles, said coating being comprised of from about 50 to 100 percent by weight of acid-insoluble lacquers soluble in intestinal juices and from about 0 to 50 percent by weight of lacquers insoluble in gastric and intestinal juices and said coating being present in an amount of from about 3 to 30 percent by weight, based on the weight of the spheroid particles, and to the preparation of such a composition.
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