Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
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United States of America Patent
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Jan 18, 1983
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N/A
app pub date -
Dec 18, 1981
filing date -
Dec 18, 1981
priority date (Note) -
Expired
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Abstract
A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration, the carrier base material being hydroxypropylmethylcellulose or a mixture of hydroxypropylmethylcellulose and up to 30% by weight of the mixture of ethylcellulose and/or up to 30% by weight of the mixture of sodium carboxymethylcellulose, and wherein the hydroxypropylmethylcellulose has a hydroxypropoxyl content of 9-12 weight % and a number average molecular weight of less than 50,000.
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