Radioimmunoassay of pterins and novel pterin derivatives useful therefor

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United States of America Patent

PATENT NO 4371514
SERIAL NO

06166519

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Abstract

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Pterin derivatives are described having the formula (I) ##STR1## wherein R represents a hydroxyphenyl group, a radioiodinated hydroxyphenyl group, a tyraminocarbonyl group, a radioiodinated tyraminocarbonyl group, a proteinocarbonyl group or a carboxy group; Q represents a straight or branched chain alkylene group having 1 to 6 carbon atoms; and R.sub.6 and R.sub.7 each represents a hydrogen, an alkyl group having from 1 to 6 carbon atoms, a hydroxyalkyl group having from 1 to 6 carbon atoms; and a radioimmunoassay method is described using a radioiodinated 4-hydroxy-2-tyraminopteridine derivative or a radioiodinated 4-hydroxy-2-tyraminocarbonylalkylaminopteridine derivative as the tracer.

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Patent Owner(s)

  • DAIICHI RADIOISOTOPE LABORATORIES, LTD.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akino, Miki Musashino, JP 1 11
Kato, Takeshi Yokohama, JP 265 4274
Matsuura, Sadao Nagoya, JP 1 11
Nagatsu, Toshiharu Yokohama, JP 7 37
Sugimoto, Takashi Chiryu, JP 76 377
Yamaguchi, Tokio Hachioji, JP 3 27

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