Pyridoxine derivatives, and use in therapeutics
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United States of America Patent
Stats
-
Feb 22, 1983
Grant Date -
N/A
app pub date -
May 11, 1981
filing date -
May 19, 1980
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Novel pyridoxine derivatives represented by the general formula: ##STR1## in which: R represents a radical ##STR2## --CH.sub.2 --(CH.sub.2).sub.n --CH.sub.2 --OR.sub.2 or ##STR3## in which n represents 0 or 1, X and X.sub.1, which are different, represent hydrogen or methyl, Y represents hydrogen or methyl and R.sub.2 represents a phenyl group non-substituted or bearing one or two substituents selected from the group consisting of fluorine, chlorine and bromine and of the radicals methyl, ethyl, n-propyl, isopropyl and methoxy, R.sub.1 represents hydrogen or a radical of formula ##STR4## in which R.sub.3 represents a straight-chain alkyl radical having from 1 to 4 carbon atoms and pharmaceutically acceptable acid addition salts thereof. These compounds present .alpha.-antiadrenergic properties some of them also presenting .beta.-antiadrenergic, antihypertensive and central depressant effects.
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
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| Patent Owner | Address | |
|---|---|---|
| S A LABAZ-SANOFI N V | Not Provided |
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Inventor(s)
| Inventor Name | Address | # of filed Patents | Total Citations |
|---|---|---|---|
| Descamps, Marcel | Rosieres, BE | 20 | 282 |
| Urbain, deceased Marcel | late of Waterloo, BE | 1 | 31 |
| Urbain, legal representative Claire | Waterloo, BE | 1 | 31 |
| Urbain, legal representative Jacques J Z | Lasne, BE | 1 | 31 |
| Urbain, legal representative Jean P M C | Waterloo, BE | 1 | 31 |
| Urbain, legal representative Nadine C J | Waterloo, BE | 1 | 31 |
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| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
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