Pyridoxine derivatives, and use in therapeutics

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United States of America Patent

PATENT NO 4374841
SERIAL NO

06262449

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Novel pyridoxine derivatives represented by the general formula: ##STR1## in which: R represents a radical ##STR2## --CH.sub.2 --(CH.sub.2).sub.n --CH.sub.2 --OR.sub.2 or ##STR3## in which n represents 0 or 1, X and X.sub.1, which are different, represent hydrogen or methyl, Y represents hydrogen or methyl and R.sub.2 represents a phenyl group non-substituted or bearing one or two substituents selected from the group consisting of fluorine, chlorine and bromine and of the radicals methyl, ethyl, n-propyl, isopropyl and methoxy, R.sub.1 represents hydrogen or a radical of formula ##STR4## in which R.sub.3 represents a straight-chain alkyl radical having from 1 to 4 carbon atoms and pharmaceutically acceptable acid addition salts thereof. These compounds present .alpha.-antiadrenergic properties some of them also presenting .beta.-antiadrenergic, antihypertensive and central depressant effects.

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Patent Owner(s)

Patent OwnerAddress
S A LABAZ-SANOFI N VNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Descamps, Marcel Rosieres, BE 20 282
Urbain, deceased Marcel late of Waterloo, BE 1 31
Urbain, legal representative Claire Waterloo, BE 1 31
Urbain, legal representative Jacques J Z Lasne, BE 1 31
Urbain, legal representative Jean P M C Waterloo, BE 1 31
Urbain, legal representative Nadine C J Waterloo, BE 1 31

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