Macromolecular environment control in specific receptor assays
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United States of America Patent
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Feb 22, 1983
Issued Date -
N/A
app pub date -
Feb 9, 1981
filing date -
Nov 24, 1978
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Method and compositions are provided for performing protein binding assays involving a homologous pair consisting of ligand and receptor for the ligand. The method employs a label conjugated to a member of said homologous pair and a uniformly dispersed discontinuous phase of discrete particles in a continuous aqueous phase, where the discrete particles create microenvironments which allow for discrimination between the label associated with the particle--in a discontinuous phase--and the label in the continuous phase. Various conjugates and particles are provided which find use in the subject method.
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