Therapeutic agents for preventing phospholipid degradation and free fatty acid proliferation

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United States of America Patent

PATENT NO 4386078
SERIAL NO

06303505

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed is a method for substantially maintaining glycerophospholipid production by cells and for suppressing consequent free fatty acid proliferation in said cells wherein injury or disease has caused normal glycerophospholipid production of said cells to become retarded. Such method comprises presenting said cell with CDP-ethanolamine, CDP-N-methylethanolamine, CDP-N,N-dimethylethanolamine, mixtures thereof or mixtures of these compounds with CDP-choline . Injuries or diseases to which the method has applicability include ischemia, heart disease, stroke, and spinal cord injury. The CDP-compounds may be administered either before or after the onset of the injury or disease.

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Patent Owner(s)

  • THE OHIO STATE UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dabrowiecki, Zbigniew M Warsaw, PL 1 5
Dorman, Robert V Columbus, OH 1 5
Horrocks, Lloyd A Columbus, OH 1 5

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