4-Pregnene-derivatives, a process for their preparation, composition and method for the treatment of inflammatory conditions
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United States of America Patent
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Sep 13, 1983
Grant Date -
N/A
app pub date -
Nov 17, 1981
filing date -
Dec 4, 1980
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention refers to compounds having anti-inflammatory activity, characterized by the formula ##STR1## in the form of a stereoisomeric mixture or an epimer of the R or S type regarding the orientation of the substituents at the carbon atom in position 22, in which formula A is n-propyl or n-butyl and Z is hydroxyl or hydroxyl esterified with a fatty acid with a straight or branched hydrocarbon chain having 1-5 carbon atoms. The invention also refers to a process for the preparation of these compounds, a pharmaceutical preparation containing one of the compounds and a method for the treatment and control of inflammatory conditions.
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