Anthracycline synthesis

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United States of America Patent

PATENT NO 4405522
SERIAL NO

06340434

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A synthesis of 5,12-dihydroxy-1,3,4-trihydro-2,6,11-tetracenetrione and its derivatives from leucoquinizarin or a derivative of leucoquinizarin. The tetracenetriones are well-known intermediates in the synthesis of compounds related to doxorubicin.

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UNIVERSITY OF KANSAS CENTER FOR RESEARCH INCORPORATED THE A NOT FOR PROFIT CORP OF KANSASNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mitscher, Lester A Lawrence, KS 13 64

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