Analgesic 5-oxygenated-6,7-benzomorphan derivatives

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United States of America Patent

PATENT NO 4425353
SERIAL NO

06282799

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Abstract

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6,7-Benzomorphan derivatives of formula I, ##STR1## wherein R.sub.1 is hydrogen; optionally hydroxy- and/or alkoxy-substituted alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkylalkyl; alkenyloxyalkyl, aralkyl, arylhydroxyalkyl, aralkenyl or tetrahydrofurylalkyl; or optionally alkyl-substituted furylalkyl or isoxazolylalkyl, R.sub.2 is hydrogen or methyl, R.sub.3 is hydrogen, alkyl, alkenyl, alkynyl, aralkyl, hydroxyalkyl of alkoxyalkyl and R.sub.4 is hydrogen, hydroxy, alkoxy or alkenyloxy, hydroxy groups in said compounds being each optionally acylated, having analgesic and luteinising hormone secretion inhibiting properties.

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Patent Owner(s)

Patent OwnerAddress
ACF CHEMIEFARMA NVMAARSSEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akkerman, Antony M Amsterdam, NL 5 35
Smit, Roelof C K Maarssen, NL 1 5
van, Bakel Hermanus C C K Montfoort, NL 4 14

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