Antihypercholesterolemic compounds
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United States of America Patent
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Apr 24, 1984
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N/A
app pub date -
Dec 18, 1980
filing date -
Aug 5, 1980
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Expired
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Abstract
6(R)-[2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)-polyhydronaphthyl-1')-ethyl]-4 (R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones are prepared by acylation of the corresponding 8'-hydroxy compounds. The products are strong inhibitors of the biosynthesis of cholesterol.
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