Naphthalenylthiazole derivatives
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United States of America Patent
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May 1, 1984
Grant Date -
N/A
app pub date -
Sep 21, 1982
filing date -
Sep 21, 1982
priority date (Note) -
Expired
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Abstract
Disclosed herein are new aldose reductase inhibitors of the formula ##STR1## wherein R is ##STR2## wherein R.sup.1 is lower alkyl; R.sup.2 is halo and R.sup.3 is hydrogen, or R.sup.2 and R.sup.3 each is a substituent at positions 3, 4, 5 or 6 of the naphthalene ring selected from the group consisting of lower alkoxy, trihalomethyl, and halo; and R.sup.4 is lower alkyl. The derivatives are useful for treating or preventing diabetic complications.
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